A murine Ig light chain transgene reveals IGKV3 gene contributions to anti‐collagen types IV and II specificities
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DOI: 10.1016/j.molimm.2017.08.015
Abstract: HighlightsIGKV3‐encoded light chains are prominent among murine anti‐type II and anti‐type IV collagen autoantibodies.Mice bearing an IGKV3 light chain transgene develop subsets of B cells reactive with each collagen.IGKV3 subgroup genes contribute structural fitness to… read more here.
Keywords: collagen; igkv3; anti collagen; light chain ... See more keywords