Anti‐IgLON5 Disease Responsive to Immunotherapy: A Case Report with an Abnormal MRI
Sign Up to like & getrecommendations! Published in 2018 at "Movement Disorders Clinical Practice"
DOI: 10.1002/mdc3.12679
Abstract: A 65-year-old man presented with a 3-month history of gait disturbance, generalized chorea, and painful intermittent cervical dystonia. He also reported sleep disruption, mood changes, and irritability. He had a medical history of hypertension and… read more here.
Keywords: responsive immunotherapy; iglon5 disease; disease responsive; disease ... See more keywords
Unusual Head Movements in Anti‐IgLON5 Disease
Sign Up to like & getrecommendations! Published in 2020 at "Movement Disorders Clinical Practice"
DOI: 10.1002/mdc3.13016
Abstract: Anti-IgLON5 disease is a clinically heterogenous condition characterized by prominent sleep disorders, preceded or accompanied by neurological signs and symptoms, and the presence of IgLON5 antibodies. We present a case of a fluctuating segmental dystonia… read more here.
Keywords: head; movement; iglon5 disease; disease ... See more keywords
Disentangling the Phenotypes of Anti‐IgLON5 Disease: When Clinical Suspicion Matters
Sign Up to like & getrecommendations! Published in 2022 at "Movement Disorders Clinical Practice"
DOI: 10.1002/mdc3.13446
Abstract: restriction in those with a PSP-like phenotype. These fi ndings are in line with the previously reported absence of square wave jerks among the oculomotor abnormalities of anti-IgLON5 patients compared to PSP. 6 The presence… read more here.
Keywords: disease clinical; disease; anti iglon5; phenotypes anti ... See more keywords
Expanding the clinical spectrum of anti-IgLON5 disease: A multicenter retrospective study.
Sign Up to like & getrecommendations! Published in 2021 at "European journal of neurology"
DOI: 10.1111/ene.15117
Abstract: BACKGROUND We conducted this study to describe detailed clinical characteristics, ancillary test results and treatment response of a group of Chinese patients with anti-IgLON5 disease. METHODS We recruited 13 patients with positive IgLON5 antibodies in… read more here.
Keywords: spectrum anti; iglon5 disease; anti iglon5;
Further insights into anti-IgLON5 disease: a case with complex clinical presentation
Sign Up to like & getrecommendations! Published in 2024 at "BMC Neurology"
DOI: 10.1186/s12883-024-03837-3
Abstract: Anti-IgLON5 disease is an autoimmune encephalitis overlapping with neurodegenerative disorders due to pathological accumulation of hyperphosphorylated tau. It is characterized by several clinical manifestations determined by involvement of different brain areas, and mild response to… read more here.
Keywords: case complex; semiology; anti iglon5; iglon5 disease ... See more keywords
Anti-IgLON5 Disease – The Current State of Knowledge and Further Perspectives
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.852215
Abstract: Anti-IgLON5 disease is a relatively new neurological entity with the first cases reported in 2014. So far, less than 70 articles on this topic have been published. Due to its unspecific symptomatology, diverse progression, novelty… read more here.
Keywords: symptomatology; anti iglon5; knowledge; disease current ... See more keywords
Figural Memory Impairment in Conjunction With Neuropsychiatric Symptoms in IgLON5 Antibody-Associated Autoimmune Encephalitis
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Psychiatry"
DOI: 10.3389/fpsyt.2020.00576
Abstract: Background IgLON5 disease is an autoimmune disorder that shares neuropathological aspects with a tauopathy. Its clinical spectrum is heterogeneous, and figural memory impairment as an initial phenomenon of IgLON5 syndrome has not yet been described.… read more here.
Keywords: autoimmune encephalitis; iglon5 disease; memory impairment; figural memory ... See more keywords
Causes of Death in Anti-IgLON5 Disease: A Novel Case Report and Systematic Literature Review
Sign Up to like & getrecommendations! Published in 2025 at "Brain Sciences"
DOI: 10.3390/brainsci15090921
Abstract: Background/Objectives: Anti-IgLON5 disease is a neurological disorder characterized by the presence of autoantibodies directed against the neuronal cell adhesion protein IgLON5. Pathophysiology involves both autoimmune inflammation and neurodegenerative processes. The most common causes of death… read more here.
Keywords: causes death; anti iglon5; case; iglon5 disease ... See more keywords
The Expanding Spectrum of Anti-IgLON5 Disease: A Case Series from an Indian Cohort
Sign Up to like & getrecommendations! Published in 2025 at "Annals of Indian Academy of Neurology"
DOI: 10.4103/aian.aian_1073_24
Abstract: Anti-IgLON5 disease is an evolving entity that lies at the confluence of autoimmunity and neurodegeneration. Reports from India remain sparse. In this series, we describe seven Indian patients with anti-IgLON5–related disease. Patients presented across the… read more here.
Keywords: disease; anti iglon5; spectrum; series ... See more keywords