Abstract 518: Agonistic Death Receptor 5 (DR5) IgM antibody IGM-8444 induces tumor cell apoptosisin vitroandin vivoand has a favorablein vitrosafety profile
Sign Up to like & getrecommendations! Published in 2020 at "Cancer Research"
DOI: 10.1158/1538-7445.am2020-518
Abstract: Death receptor 5 (DR5) is a member of the tumor necrosis factor (TNF) receptor superfamily that binds TNF-related apoptosis inducing ligand (TRAIL) to induce receptor trimerization and activate extrinsic apoptotic pathways. DR5 is expressed on… read more here.
Keywords: igm 8444; dr5; receptor; cell ... See more keywords