IGNYTE-ESO: A master protocol to assess safety and activity of letetresgene autoleucel (lete-cel; GSK3377794) in HLA-A*02+ patients with synovial sarcoma or myxoid/round cell liposarcoma (Substudies 1 and 2).
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DOI: 10.1200/jco.2021.39.15_suppl.tps11582
Abstract: • Unlike CAR-T cells that recognize cell surface proteins, T-cell receptors can recognize antigenic epitopes of intracellular proteins that are processed and presented on the surface of the cancer cell in the context of human… read more here.
Keywords: ignyte eso; cell; master protocol; hla ... See more keywords