Evaluation of a lateral flow assay–based IFN-γ release assay as a point-of-care test for the diagnosis of latent tuberculosis infection
Sign Up to like & getrecommendations! Published in 2021 at "Clinical Rheumatology"
DOI: 10.1007/s10067-021-05663-1
Abstract: We compared the performance of a fluorescence lateral flow assay (ichroma™ IGRA-TB) with the QuantiFERON-TB Gold PLUS (QFT-PLUS) for the diagnosis of latent tuberculosis infection (LTBI) in patients with immune-mediated inflammatory diseases (IMID) prior to… read more here.
Keywords: igra; ichroma igra; flow assay; lateral flow ... See more keywords
IMPACT OF COMORBIDITIES ON THE PERFORMANCE OF INTERFERON GAMMA RELEASE ASSAY IN A GREEK ELDERLY POPULATION WITHOUT OVERT IMMUNODEFICIENCY.
Sign Up to like & getrecommendations! Published in 2020 at "International journal of antimicrobial agents"
DOI: 10.1016/j.ijantimicag.2020.106073
Abstract: Background The prevalence of latent Tuberculosis Infection (LTBI) increases with aging. Interferon gamma release assay (IGRA) is a T-cell based assay, widely used for the detection of LTBI. Objectives To identify the prevalence of LTBI… read more here.
Keywords: release assay; gamma release; interferon gamma; igra ... See more keywords
Comparing the cost-effectiveness of two screening strategies for latent tuberculosis infection in Portugal.
Sign Up to like & getrecommendations! Published in 2021 at "Pulmonology"
DOI: 10.1016/j.pulmoe.2021.04.002
Abstract: INTRODUCTION AND OBJECTIVES Screening for latent tuberculosis infection (LTBI) in close contacts of infectious TB cases might include Tuberculin Skin Test (TST) and Interferon-Gamma Release Assays (IGRA), in combination or as single-tests. In Portugal, the… read more here.
Keywords: igra; cost; strategy; cost effectiveness ... See more keywords
DAR-901 vaccine for the prevention of infection with Mycobacterium tuberculosis among BCG-immunized adolescents in Tanzania: A randomized controlled, double-blind phase 2b trial.
Sign Up to like & getrecommendations! Published in 2020 at "Vaccine"
DOI: 10.1016/j.vaccine.2020.09.055
Abstract: BACKGROUND SRL172 prevented disease due to Mycobacterium tuberculosis in a Phase 3 trial. DAR-901 represents a scalable manufacturing process for SRL172. We sought to determine if DAR-901 would prevent infection with M. tuberculosis among BCG-primed… read more here.
Keywords: dar 901; trial; dar; infection ... See more keywords
P32 Should we continue to test for latent tuberculosis infection in patients treated with biologics?
Sign Up to like & getrecommendations! Published in 2020 at "Rheumatology"
DOI: 10.1093/rheumatology/keaa111.031
Abstract: Timely diagnosis of tuberculosis (TB) infection is important in patients receiving biologics. Current BSR guidelines on biologic safety in inflammatory arthritis (2018) advise to screen all patients for TB before starting treatment. Due to limitations… read more here.
Keywords: risk; cxr; infection; rheumatology ... See more keywords
Interferon-γ release assay as a sensitive diagnostic tool of latent tuberculosis infection in patients with HIV: a cross-sectional study
Sign Up to like & getrecommendations! Published in 2018 at "BMC Infectious Diseases"
DOI: 10.1186/s12879-018-3508-8
Abstract: BackgroundIn developing countries, tuberculosis (TB) is a major public health problem and the leading cause of death among patients with HIV (Human Immunodeficiency Virus). Until 2001, the tuberculin skin test (TST) was the only available… read more here.
Keywords: patients hiv; risk; tuberculosis; ltbi ... See more keywords
Interferon gamma release assay tests are associated with persistence and completion of latent tuberculosis infection treatment in the United States: Evidence from commercial insurance data
Sign Up to like & getrecommendations! Published in 2020 at "PLoS ONE"
DOI: 10.1371/journal.pone.0243102
Abstract: Background Risk-targeted testing and treatment of latent tuberculosis infection (LTBI) is a critical component of the United States’ (US) tuberculosis (TB) elimination strategy, but relatively low treatment completion rates remain a challenge. Both treatment persistence… read more here.
Keywords: completion; treatment; persistence completion; igra ... See more keywords
Prevalence of Mycobacterium tuberculosis infection as measured by the QuantiFERON-TB Gold assay and ESAT-6 free IGRA among adolescents in Mwanza, Tanzania
Sign Up to like & getrecommendations! Published in 2021 at "PLoS ONE"
DOI: 10.1371/journal.pone.0252808
Abstract: Background The prevalence of latent tuberculosis infection (LTBI) is vastly higher than that of tuberculosis (TB) disease and this enormous reservoir of individuals with LTBI impacts the global TB control strategy. Adolescents are at greatest… read more here.
Keywords: infection; prevalence; free igra; qft git ... See more keywords
Correlation between tuberculosis-specific interferon-γ release assay and intrathoracic calcification: A cross-sectional study
Sign Up to like & getrecommendations! Published in 2022 at "PLoS ONE"
DOI: 10.1371/journal.pone.0270785
Abstract: Background Although persistent tuberculosis (TB) infection is known to cause calcification in the lungs, the relationship between intrathoracic calcification and the results of the interferon-γ release assay (IGRA) has not been fully elucidated. This study… read more here.
Keywords: intrathoracic calcification; calcification; tuberculosis; igra results ... See more keywords
Impact of Immunosuppressive Therapy on the Performance of Latent Tuberculosis Screening Tests in Patients with Inflammatory Bowel Disease: A Systematic Review and Meta-Analysis
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Personalized Medicine"
DOI: 10.3390/jpm12030507
Abstract: Screening for latent tuberculosis infection (LTBI) is mandatory before commencing tumor necrosis factor (TNF)-α inhibitor use. However, the impact of immunosuppressive therapy (IST), including corticosteroids and immunomodulators, on the performance of LTBI screening in patients… read more here.
Keywords: impact immunosuppressive; rate; ist; performance ... See more keywords
The Interferon-Gamma Release Assay versus the Tuberculin Skin Test in the Diagnosis of Mycobacterium tuberculosis Infection in BCG-Vaccinated Children and Adolescents Exposed or Not Exposed to Contagious TB
Sign Up to like & getrecommendations! Published in 2023 at "Vaccines"
DOI: 10.3390/vaccines11020387
Abstract: Background: Children have an increased risk of developing active tuberculosis (TB) after exposure to Mycobacterium tuberculosis (M.tb), and they are more likely to develop the most severe forms of TB. Rapid diagnosis and treatment of… read more here.
Keywords: igra; exposed contagious; tst; adolescents exposed ... See more keywords