Inhibition of myosin IIA-actin interaction prevents ischemia/reperfusion induced cardiomyocytes apoptosis through modulating PINK1/Parkin pathway and mitochondrial fission.
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DOI: 10.1016/j.ijcard.2018.04.079
Abstract: BACKGROUND Mitochondrial fission is the essential mechanisms of myocardial ischemia/reperfusion (MI/R)-induced cardiomyocytes apoptosis. Myosin II plays a key role in fission due to the recruitment and actomyosin constriction at the fission site in U2OS cells.… read more here.
Keywords: myosin; fission; myosin iia; iia actin ... See more keywords