α-actinin-4 drives invasiveness by regulating myosin IIB expression and myosin IIA localization.
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DOI: 10.1242/jcs.258581
Abstract: The mechanisms by which the mechanoresponsive actin crosslinking protein α-actinin-4 (ACTN4) regulates cell motility and invasiveness remains incompletely understood. Here we show that in addition to regulating protrusion dynamics and focal adhesion formation, ACTN4 transcriptionally… read more here.
Keywords: myosin iib; myosin; expression; iib expression ... See more keywords