AGK Potentiates Arterial Thrombosis by Affecting Talin-1 and αIIbβ3-Mediated Bidirectional Signaling Pathway
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DOI: 10.1161/atvbaha.122.318647
Abstract: Background: AGK (acylglycerol kinase) was first identified as a mitochondrial transmembrane protein that exhibits a lipid kinase function. Recent studies have established that AGK promotes cancer growth and metastasis, enhances glycolytic metabolism and function fitness… read more here.
Keywords: iib mediated; mediated bidirectional; agk; talin ... See more keywords
Characterization of Integrin αIIbβ3-Mediated Outside-in Signaling by Protein Kinase Cδ in Platelets
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DOI: 10.3390/ijms21186563
Abstract: Engagement of integrin αIIbβ3 promotes platelet–platelet interaction and stimulates outside-in signaling that amplifies activation. Protein kinase Cδ (PKCδ) is known to play an important role in platelet activation, but its role in outside-in signaling has… read more here.
Keywords: iib mediated; integrin iib; outside signaling; role ... See more keywords