Prodrug-inspired adenosine triphosphate–activatable celastrol-Fe(III) chelate for cancer therapy
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DOI: 10.1126/sciadv.adn0960
Abstract: Celastrol (CEL), an active compound isolated from the root of Tripterygium wilfordii, exhibits broad anticancer activities. However, its poor stability, narrow therapeutic window and numerous adverse effects limit its applications in vivo. In this study,… read more here.
Keywords: celastrol; iii chelate; cel; adenosine triphosphate ... See more keywords