Free Composite Serratus Anterior-Latissimus-Rib Flaps for Acute One-Stage Reconstruction of Gustilo IIIB Tibia Fractures.
Sign Up to like & getrecommendations! Published in 2018 at "American journal of orthopedics"
DOI: 10.12788/ajo.2018.0047
Abstract: Gustilo IIIB injuries of the tibia with segmental bone loss continue to be a difficult reconstructive problem. The serratus anterior-latissimus-rib (SALR) composite flap consists of bone and muscle; this flap can provide soft tissue coverage… read more here.
Keywords: tibia fractures; gustilo; tissue; tibia ... See more keywords
Heparan Sulfate, Mucopolysaccharidosis IIIB and Sulfur Metabolism Disorders
Sign Up to like & getrecommendations! Published in 2022 at "Antioxidants"
DOI: 10.3390/antiox11040678
Abstract: Mucopolysaccharidosis, type IIIB (MPS IIIB) is a rare disease caused by mutations in the N-alpha-acetylglucosaminidase (NAGLU) gene resulting in decreased or absent enzyme activity. On the cellular level, the disorder is characterized by the massive… read more here.
Keywords: metabolism; heparan sulfate; mucopolysaccharidosis; level ... See more keywords
Substrate-Based Design of Cytosolic Nucleotidase IIIB Inhibitors and Structural Insights into Inhibition Mechanism
Sign Up to like & getrecommendations! Published in 2022 at "Pharmaceuticals"
DOI: 10.3390/ph15050554
Abstract: Cytosolic nucleotidases (cNs) catalyze dephosphorylation of nucleoside 5’-monophosphates and thereby contribute to the regulation of nucleotide levels in cells. cNs have also been shown to dephosphorylate several therapeutically relevant nucleotide analogues. cN-IIIB has shown in… read more here.
Keywords: based design; inhibition; substrate based; iiib inhibitors ... See more keywords