Outcomes of CD19 chimeric antigen receptor T cell followed by haploidentical hematopoietic stem-cell transplantation in relapsed/refractory B-cell acute lymphoblastic leukemia with IKZF1 deletion
Sign Up to like & getrecommendations! Published in 2022 at "Bone Marrow Transplantation"
DOI: 10.1038/s41409-021-01554-w
Abstract: TO THE EDITOR: Acute lymphoblastic leukemia (ALL) is a clinically and genetically heterogeneous hematopoietic malignancy, and 75% of ALL cases in adults are of B-cell lineage [1]. The Ikaros protein plays a vital role in… read more here.
Keywords: cd19 car; treatment; car cell; cell ... See more keywords
Cuplike nuclear morphology is highly associated with IKZF1 deletion in pediatric precursor B-cell ALL.
Sign Up to like & getrecommendations! Published in 2019 at "Blood"
DOI: 10.1182/blood.2019000604
Abstract: TO THE EDITOR: Cuplike nuclei (CLN) (nuclei with prominent invagination) are recognized as a distinctive morphologic finding in the blasts of acute myeloid leukemia (AML).[1][1][⇓][2][⇓][3][⇓][4][⇓][5]-[6][6] They are seen in ∼20% of all AML cases[2][2],[4][4],[5][5] and… read more here.
Keywords: highly associated; associated ikzf1; cuplike nuclear; ikzf1 deletion ... See more keywords