Dual IKZF2 and CK1α degrader targets acute myeloid leukemia cells.
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DOI: 10.1182/blood-2022-167678
Abstract: Acute myeloid leukemia (AML) is a hematologic malignancy for which several epigenetic regulators have been identified as therapeutic targets. Here we report the development of cereblon-dependent degraders of IKZF2 and casein kinase 1α (CK1α), termed… read more here.
Keywords: ikzf2 ck1; myeloid leukemia; acute myeloid; ikzf2 ... See more keywords