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   Articles with "il10" as a keyword



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Overexpression of interleukin‐10 in engineered macrophages protects endothelial cells against LPS‐induced injury in vitro

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recommendations! Published in 2022 at "FEBS Open Bio"

DOI: 10.1002/2211-5463.13365

Abstract: Endothelial dysfunction is a primary pathophysiological change in sepsis. Macrophages are known to interact with vascular endothelial cells during the development of sepsis. Recently, drug delivery based on engineered macrophages was reported as an alternative… read more here.

Keywords: engineered macrophages; endothelial cells; lps induced; cells lps ... See more keywords
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Common gene variants within 3′‐untranslated regions as modulators of multiple myeloma risk and survival

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recommendations! Published in 2020 at "International Journal of Cancer"

DOI: 10.1002/ijc.33377

Abstract: We evaluated the association between germline genetic variants located within the 3′‐untranlsated region (polymorphic 3′UTR, ie, p3UTR) of candidate genes involved in multiple myeloma (MM). We performed a case‐control study within the International Multiple Myeloma… read more here.

Keywords: risk; il10; myeloma; multiple myeloma ... See more keywords
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Short‐term exercise training reduces anti‐inflammatory action of interleukin‐10 in adults with obesity

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recommendations! Published in 2018 at "Cytokine"

DOI: 10.1016/j.cyto.2018.05.035

Abstract: HighlightsIL10 and IL6 have anti‐inflammatory effects in whole‐blood cultures.The anti‐inflammatory action of IL10 was more potent than IL6.MICT and to a greater extent HIIT reduced anti‐inflammatory IL10 action.HIIT and MICT differentially affected IL6 function.Short‐term exercise… read more here.

Keywords: anti inflammatory; il10; hiit; il6 ... See more keywords
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Carp Il10a and Il10b exert identical biological activities in vitro, but are differentially regulated in vivo

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recommendations! Published in 2017 at "Developmental and Comparative Immunology"

DOI: 10.1016/j.dci.2016.08.016

Abstract: ABSTRACT We recently reported on the functional characterization of carp Il10. We showed that carp Il10 is able to downregulate proinflammatory activities by carp phagocytes and promote B cell proliferation, differentiation and antibody production as… read more here.

Keywords: il10a il10b; il10; differentially regulated; il10b ... See more keywords
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Association of anti-inflammatory cytokine IL10 polymorphisms with motoric cognitive risk syndrome in an Ashkenazi Jewish population

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recommendations! Published in 2017 at "Neurobiology of Aging"

DOI: 10.1016/j.neurobiolaging.2017.06.006

Abstract: Motoric cognitive risk (MCR) syndrome is a newly described predementia syndrome characterized by the presence of cognitive complaints and slow gait, which is associated with increased risk of conversion to dementia. The underlying biological mechanisms… read more here.

Keywords: cytokine il10; il10; risk; ashkenazi jewish ... See more keywords
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F8-IL10: A New Potential Antirheumatic Drug Evaluated by a PET-Guided Translational Approach

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recommendations! Published in 2019 at "Molecular Pharmaceutics"

DOI: 10.1021/acs.molpharmaceut.8b00982

Abstract: Antibody fragment F8-mediated interleukin 10 (IL10) delivery is a novel treatment for rheumatoid arthritis (RA). F8 binds to the extra-domain-A of fibronectin (ED-A). In this study, in vivo biodistribution and arthritis targeting of radiolabeled F8-IL10… read more here.

Keywords: il10; 124i il10; pet guided; new potential ... See more keywords
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Anti-inflammatory cytokine IL10 loaded cRGD liposomes for the targeted treatment of atherosclerosis

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recommendations! Published in 2020 at "Journal of Microencapsulation"

DOI: 10.1080/02652048.2020.1836058

Abstract: Abstract Aim Atherosclerosis (AS) is one of the main causes of cardiovascular disease which might lead to myocardial infarction or stroke and further leads to fatality. Method In this study, we have designed an anti-inflammatory… read more here.

Keywords: anti inflammatory; il10; il10 crgd; inflammatory cytokine ... See more keywords
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Genetic variation in human IL10 proximal promoter and susceptibility to HIV-1 infection in Mali, West Africa.

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recommendations! Published in 2020 at "AIDS research and human retroviruses"

DOI: 10.1089/aid.2020.0140

Abstract: It is now recognized that in order to fully understand the role of host genetic variation on susceptibility to HIV-1 infection, investigations must be extended to African populations. We sought to determine if genetic variation… read more here.

Keywords: hiv infection; hiv; genetic variation; il10 ... See more keywords

The Synergistic Effect of TNFA and IL10 Promoter Polymorphisms on Genetic Predisposition to Systemic Lupus Erythematosus.

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recommendations! Published in 2018 at "Genetic testing and molecular biomarkers"

DOI: 10.1089/gtmb.2017.0169

Abstract: AIMS We investigated the individual and combined effect of functional TNFA -308G/A and IL10 -1082G/A single nucleotide polymorphisms (SNPs) and their genotypes on the susceptibility to systemic lupus erythematosus (SLE) in a Bulgarian population. MATERIALS… read more here.

Keywords: tnfa; il10; systemic lupus; lupus erythematosus ... See more keywords
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Interleukin-10 and its receptors at the maternal–conceptus interface: expression, regulation, and implication for T helper 2 cytokine predominance and maternal immune tolerance in the pig, a true epitheliochorial placentation species

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recommendations! Published in 2022 at "Biology of Reproduction"

DOI: 10.1093/biolre/ioac058

Abstract: Abstract The appropriate balance between pro-inflammatory and anti-inflammatory cytokines is important for the maternal immune tolerance during pregnancy in mammals. Among the various cytokines, interleukin (IL)-10 (IL10) plays an essential role in anti-inflammatory responses, while… read more here.

Keywords: conceptus interface; expression; pregnancy; maternal conceptus ... See more keywords
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MO912INMUNE STATUS ON HAEMODIALYSIS PATTIENTS AFFECTED WITH COVID19 INFECTION

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recommendations! Published in 2021 at "Nephrology Dialysis Transplantation"

DOI: 10.1093/ndt/gfab102.0013

Abstract: Abstract Background and Aims End-stage renal disease patients on haemodialysis (HD) seem more likely to develop severe COVID19 disease. Over the course of COVID disease, we observed a poor tolerance to HD sessions with a… read more here.

Keywords: status; il10; haemodialysis; infection ... See more keywords