Xenopus laevis il11ra.L is an experimentally proven interleukin-11 receptor component that is required for tadpole tail regeneration
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DOI: 10.1038/s41598-022-05954-w
Abstract: Xenopus laevis tadpoles possess high regenerative ability and can regenerate functional tails after amputation. An early event in regeneration is the induction of undifferentiated cells that form the regenerated tail. We previously reported that interleukin-11… read more here.
Keywords: tail regeneration; il11ra; il11; receptor ... See more keywords
Abstract 3993: In vivo efficacy of an anti-human IL11RA antibody in B-hIL11RA mice with APAP-induced liver damage
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DOI: 10.1158/1538-7445.am2023-3993
Abstract: Acetaminophen (N-acetyl-p-aminophenol; APAP) overdose is a common cause of drug-induced acute liver injury, thereby making APAP administration a frequently used experimental model due to its highly reproducible and dose-dependent hepatoxicity. APAP-induced liver injury (AILI) mouse… read more here.
Keywords: human il11ra; il11ra; anti human; vivo efficacy ... See more keywords