Current treatment strategies and recommendations in psoriatic arthritis
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Rheumatic Diseases"
DOI: 10.1111/1756-185x.14474
Abstract: Psoriatic arthritis (PsA) is a chronic inflammatory arthritis and belongs to the family of spondyloarthropathies (SpA).1 Within the family of SpA, PsA is a distinct subgroup that has diverse clinical manifestations, including peripheral arthritis, enthesitis,… read more here.
Keywords: il17; psoriatic arthritis; arthritis; strategy ... See more keywords
P088 Characterization of novel humanized IL-17 mouse preclinical platforms for the efficacy evaluation of anti-human IL17 therapeutics
Sign Up to like & getrecommendations! Published in 2019 at "Annals of the Rheumatic Diseases"
DOI: 10.1136/annrheumdis-2018-ewrr2019.77
Abstract: Career situation of first and presenting author Post-doctoral fellow. Introduction As the IL17/IL23 axis has proven pathogenic for many inflammatory conditions like rheumatoid arthritis, psoriasis, IBD, multiple sclerosis (MS) and others, IL17 inhibition is an… read more here.
Keywords: il17; mice; pathology; psoriasis ... See more keywords
IL17/IL17RA as a Novel Signaling Axis Driving Mesenchymal Stem Cell Therapeutic Function in Experimental Autoimmune Encephalomyelitis
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2018.00802
Abstract: The therapeutic effect of mesenchymal stem cells (MSCs) in multiple sclerosis (MS) and the experimental autoimmune encephalomyelitis (EAE) model has been well described. This effect is, in part, mediated through the inhibition of IL17-producing cells… read more here.
Keywords: il17ra mscs; effect; mscs; cell ... See more keywords
IL17 factors are early regulators in the gut epithelium during inflammatory response to Vibrio in the sea urchin larva
Sign Up to like & getrecommendations! Published in 2017 at "eLife"
DOI: 10.7554/elife.23481
Abstract: IL17 cytokines are central mediators of mammalian immunity. In vertebrates, these factors derive from diverse cellular sources. Sea urchins share a molecular heritage with chordates that includes the IL17 system. Here, we characterize the role… read more here.
Keywords: gut epithelium; response; il17 factors; sea urchin ... See more keywords