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   Articles with "il18" as a keyword



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Adipocytes promote interleukin-18 binding to its receptors during abdominal aortic aneurysm formation in mice.

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recommendations! Published in 2019 at "European heart journal"

DOI: 10.1093/eurheartj/ehz856

Abstract: AIMS Obesity is a risk factor of abdominal aortic aneurysm (AAA). Inflammatory cytokine interleukin-18 (IL18) has two receptors: IL18 receptor (IL18r) and Na-Cl co-transporter (NCC). In human and mouse AAA lesions, IL18 colocalizes to its… read more here.

Keywords: il18; aortic aneurysm; binding; expression ... See more keywords
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Abstract 1824: Discovery and evaluation of an anti-IL18BP antibody to enhance anti-tumor immunity

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recommendations! Published in 2023 at "Cancer Research"

DOI: 10.1158/1538-7445.am2023-1824

Abstract: Interleukin-18 (IL18) is a proinflammatory cytokine that modulates both innate and adaptive immune responses. Although recombinant mIL18 has demonstrated efficacy in mouse tumor models, recombinant human IL18 has not been efficacious in clinical studies, likely… read more here.

Keywords: anti tumor; il18bp; il18 il18bp; il18 ... See more keywords
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A pilot study evaluating GSK1070806 inhibition of interleukin-18 in renal transplant delayed graft function

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recommendations! Published in 2021 at "PLoS ONE"

DOI: 10.1371/journal.pone.0247972

Abstract: Introduction Delayed graft function (DGF) following renal transplantation is a manifestation of acute kidney injury (AKI) leading to poor long-term outcome. Current treatments have limited effectiveness in preventing DGF. Interleukin-18 (IL18), a biomarker of AKI,… read more here.

Keywords: il18; delayed graft; dgf; graft function ... See more keywords
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IL16 and IL18 gene polymorphisms in women with gestational diabetes.

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recommendations! Published in 2017 at "Ginekologia polska"

DOI: 10.5603/gp.a2017.0047

Abstract: OBJECTIVES Gestational diabetes mellitus is a carbohydrate intolerance that occurs during pregnancy. Various inflammatory mediators are considered to be risk factors leading to GDM development. Among them are pro-inflammatory cytokines, such as IL16 and IL18.… read more here.

Keywords: gestational diabetes; decreased frequency; il18; pregnant women ... See more keywords