Genetic variant rs16944 in IL1B gene is a risk factor for early-onset sepsis susceptibility and outcome in preterm infants
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DOI: 10.1007/s00011-019-01301-4
Abstract: Interleukin-1-B (IL1B) is a proinflammatory cytokine that plays an important role in sepsis. The aim of this study was to evaluate the relationships between IL1B-511G/A polymorphism and susceptibility and outcome of early-onset sepsis (EOS) in… read more here.
Keywords: sepsis; early onset; susceptibility outcome; preterm infants ... See more keywords
IL1B triggers inflammatory cytokine production in bovine oviduct epithelial cells and induces neutrophil accumulation via CCL2
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DOI: 10.1111/aji.13365
Abstract: The oviduct is essential for reproduction. We previously showed that oviduct epithelial cells (OECs) isolated from aged cows expressed higher levels of inflammatory cytokines, including interleukin (IL) 1A and IL1B. In addition, aging is associated… read more here.
Keywords: epithelial cells; accumulation; production; oviduct epithelial ... See more keywords
Excellent Diagnostic Characteristics for Ultrafast Gene Profiling of DEFA1-IL1B-LTF in Detection of Prosthetic Joint Infections
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DOI: 10.1128/jcm.00558-17
Abstract: ABSTRACT The timely and exact diagnosis of prosthetic joint infection (PJI) is crucial for surgical decision-making. Intraoperatively, delivery of the result within an hour is required. Alpha-defensin lateral immunoassay of joint fluid (JF) is precise… read more here.
Keywords: detection; pji; defa1 il1b; il1b ... See more keywords
Abstract A54: Epigenetic activated IL1B promotes tumor progression of tongue cancer
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DOI: 10.1158/2326-6074.tumimm18-a54
Abstract: Alterations in host immunity, inflammation, angiogenesis, and metabolism have been noted to be prominent clinical features in patients with head and neck squamous cell carcinoma (HNSCC). IL-1β, a prototypical inflammatory cytokine, is induced and activated… read more here.
Keywords: il1b; tumor progression; immunology; cancer ... See more keywords
The Influence of Genetic Variability in IL1B and MIR146A on the Risk of Pleural Plaques and Malignant Mesothelioma
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DOI: 10.2478/raon-2020-0057
Abstract: Abstract Background Asbestos exposure is associated with the development of pleural plaques as well as malignant mesothelioma (MM). Asbestos fibres activate macrophages, leading to the release of inflammatory mediators including interleukin 1 beta (IL-1β). The… read more here.
Keywords: risk; il1b mir146a; genetic variability; il1b ... See more keywords