IL22 Inhibits Epithelial Stem Cell Expansion in an Ileal Organoid Model
Sign Up to like & getrecommendations! Published in 2019 at "Cellular and Molecular Gastroenterology and Hepatology"
DOI: 10.1016/j.jcmgh.2018.06.008
Abstract: Background & Aims Crohn’s disease is an inflammatory bowel disease that affects the ileum and is associated with increased cytokines. Although interleukin (IL)6, IL17, IL21, and IL22 are increased in Crohn’s disease and are associated… read more here.
Keywords: cell expansion; expansion; ileal organoid; il22 ... See more keywords
Epithelial Traffic Control: IL22 Gives TA Cells the Green Light
Sign Up to like & getrecommendations! Published in 2019 at "Cellular and Molecular Gastroenterology and Hepatology"
DOI: 10.1016/j.jcmgh.2018.10.004
Abstract: he intestinal epithelial barrier is instrumental in the Tphysical separation of gut microbiota from underlying innate and adaptive immune cells and stromal cells. This “barrier” is anything but static, however, with intestinal stem cells (ISCs)… read more here.
Keywords: epithelial traffic; gastroenterology; traffic control; control il22 ... See more keywords
Interleukin 22 Signaling Regulates Acinar Cell Plasticity to Promote Pancreatic Tumor Development in Mice.
Sign Up to like & getrecommendations! Published in 2019 at "Gastroenterology"
DOI: 10.1053/j.gastro.2019.12.010
Abstract: BACKGROUND & AIMS Pancreatic ductal adenocarcinoma (PDAC) is an aggressive malignancy that invades surrounding structures and metastasizes rapidly. Although inflammation is associated with tumor formation and progression, little is known about the mechanisms of this… read more here.
Keywords: tumor development; increased expression; mice; il22 ... See more keywords
Interleukin 22 prevents lipopolysaccharide-induced preterm labor in mice†
Sign Up to like & getrecommendations! Published in 2018 at "Biology of Reproduction"
DOI: 10.1093/biolre/iox182
Abstract: Abstract Preterm birth is widespread and causes 35% of all neonatal deaths. Infants who survive face potential long-term complications. A major contributing factor of preterm birth is infection. We investigated the role of interleukin 22… read more here.
Keywords: preterm birth; infection; il22; interleukin prevents ... See more keywords
Interleukin‐22 and the diagnosis of axial spondyloarthritis
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DOI: 10.1111/1756-185x.14275
Abstract: We read with interest the published manuscript by Sagiv et al1 highlighting the place of interleukin 22 (IL22) in the diagnosis of axial spondyloarthritis (SpA). The authors found that IL22 levels were elevated in patients… read more here.
Keywords: spa; diagnosis axial; axial spa; il22 ... See more keywords
Low Intestinal IL22 Associates With Increased Transplant-Related Mortality After Allogeneic Stem Cell Transplantation
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.857400
Abstract: The role of IL-22 in adult patients undergoing allogeneic stem cell transplantation (SCT) is of major interest since animal studies showed a protective and regenerative effect of IL-22 in graft versus host disease (GvHD). However,… read more here.
Keywords: allogeneic stem; stem cell; cell transplantation; expression ... See more keywords