Expression of FFAR2 by Dendritic Cells Prevents Their Expression of IL27 and is Required For Maintenance of Mucosal Barrier and Immune Response Against Colorectal Tumors in Mice.
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DOI: 10.1053/j.gastro.2019.12.027
Abstract: BACKGROUND & AIMS Intestinal microbes and their metabolites affect development of colorectal cancer (CRC). Short-chain fatty acids are metabolites generated by intestinal microbes from dietary fiber. We investigated the mechanisms by which free fatty acid… read more here.
Keywords: ffar2; il27; colitis; apcmin mice ... See more keywords