NOD-scid IL2rĪ³null mice lacking TLR4 support human immune system development and the study of human-specific innate immunity.
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DOI: 10.1093/jleuko/qiac020
Abstract: Agents that induce inflammation have been used since the 18th century for the treatment of cancer. The inflammation induced by agents such as Toll-like receptor agonists is thought to stimulate tumor-specific immunity in patients and… read more here.
Keywords: il2r null; nod scid; immune; immunity ... See more keywords