Lack of Association of IL6 polymorphism with the susceptibility to Chagas disease in Latin American populations.
Sign Up to like & getrecommendations! Published in 2020 at "Acta tropica"
DOI: 10.1016/j.actatropica.2020.105546
Abstract: The aim of the present study was to analyze IL6 rs1800795 genetic variant in the susceptibility to Trypanosoma cruzi infection and in the development of chronic Chagas cardiomyopathy (CCC), in five independent Latin American cohorts.… read more here.
Keywords: susceptibility; il6; chagas; il6 rs1800795 ... See more keywords
Evaluating the effect of adding Fish oil to Fingolimod on TNF-α, IL1β, IL6, and IFN-γ in patients with relapsing-remitting multiple sclerosis: A double-blind randomized placebo-controlled trial
Sign Up to like & getrecommendations! Published in 2017 at "Clinical Neurology and Neurosurgery"
DOI: 10.1016/j.clineuro.2017.10.004
Abstract: OBJECTIVES Fish oil is claimed to improve outcome in multiple sclerosis (MS) through anti-inflammatory and antioxidant effects by reducing cytokines including TNF-α, IFN-γ, IL6, and IL-1β. We aimed to evaluate the efficacy of adding fish… read more here.
Keywords: il6; ifn; multiple sclerosis; adding fish ... See more keywords
Interleukin-6 and interleukin-8 serum levels in prognosis of hormone-dependent breast cancer.
Sign Up to like & getrecommendations! Published in 2018 at "Cytokine"
DOI: 10.1016/j.cyto.2018.02.019
Abstract: BACKGROUND Increasing amount of evidence points to the importance of immunity in breast cancer. The prognostic value of cytokines and their effect on tumorigenesis remains inconsistent. AIM To investigate the prognostic significance of IL6 and… read more here.
Keywords: il6; breast; breast cancer; her2 ... See more keywords
Short‐term exercise training reduces anti‐inflammatory action of interleukin‐10 in adults with obesity
Sign Up to like & getrecommendations! Published in 2018 at "Cytokine"
DOI: 10.1016/j.cyto.2018.05.035
Abstract: HighlightsIL10 and IL6 have anti‐inflammatory effects in whole‐blood cultures.The anti‐inflammatory action of IL10 was more potent than IL6.MICT and to a greater extent HIIT reduced anti‐inflammatory IL10 action.HIIT and MICT differentially affected IL6 function.Short‐term exercise… read more here.
Keywords: anti inflammatory; il10; hiit; il6 ... See more keywords
Dystrophy-associated caveolin-3 mutations reveal that caveolae couple IL6/STAT3 signaling with mechanosensing in human muscle cells
Sign Up to like & getrecommendations! Published in 2019 at "Nature Communications"
DOI: 10.1038/s41467-019-09405-5
Abstract: Caveolin-3 is the major structural protein of caveolae in muscle. Mutations in the CAV3 gene cause different types of myopathies with altered membrane integrity and repair, expression of muscle proteins, and regulation of signaling pathways.… read more here.
Keywords: il6; muscle; muscle cells; il6 stat3 ... See more keywords
IRF9 and unphosphorylated STAT2 cooperate with NF-κB to drive IL6 expression
Sign Up to like & getrecommendations! Published in 2018 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.1714102115
Abstract: Significance We describe unexpected cooperation between two cytokines that are important in regulating the growth of cancers, namely, type I interferons (IFNs) and interleukin 6 (IL6). It is well established that IL6 is vital for… read more here.
Keywords: irf9 unphosphorylated; il6; stat2; il6 expression ... See more keywords
Secretory activity of the coronary artery endothelial cells in conditions of the peritoneal dialysis
Sign Up to like & getrecommendations! Published in 2022 at "Renal Failure"
DOI: 10.1080/0886022x.2021.2023024
Abstract: Abstract Introduction Endothelial dysfunction is frequent in patients treated with peritoneal dialysis and may lead to cardiac complications. We evaluated the effect of effluent dialysates and serum on the function of coronary artery endothelial cells… read more here.
Keywords: endothelial cells; peritoneal dialysis; pai; il6 ... See more keywords
Expression Pattern of Inflammatory and Anti-Inflammatory Cytokines and Key Differential Transcription Factors in Peripheral Blood Mononuclear Cells of Iranian Coronavirus Disease 2019 Patients with Different Disease Severity.
Sign Up to like & getrecommendations! Published in 2022 at "Viral immunology"
DOI: 10.1089/vim.2021.0224
Abstract: The purpose of this research was to investigate the gene expression levels of inflammatory cytokines interferon (IFN)γ, tumor necrosis factor (TNF)α, interleukin (IL)1β, IL2, IL6, IL8, and IL17, and anti-inflammatory cytokines IL4, IL10, IFNα, and… read more here.
Keywords: disease; il6; expression; inflammatory cytokines ... See more keywords
Senescence promotes in vivo reprogramming through p16INK 4a and IL‐6
Sign Up to like & getrecommendations! Published in 2018 at "Aging Cell"
DOI: 10.1111/acel.12711
Abstract: Cellular senescence is a damage response aimed to orchestrate tissue repair. We have recently reported that cellular senescence, through the paracrine release of interleukin‐6 (IL6) and other soluble factors, strongly favors cellular reprogramming by Oct4,… read more here.
Keywords: vivo reprogramming; senescence promotes; il6; senescence ... See more keywords
Expression of interleukin-6 in synovial tissue of patients with polymyalgia rheumatica
Sign Up to like & getrecommendations! Published in 2022 at "Annals of the Rheumatic Diseases"
DOI: 10.1136/ard-2022-222873
Abstract: Polymyalgia rheumatica (PMR) is a common, rheumatic inflammatory disease causing debilitating pain and stiffness of the shoulder and hip girdle. Inflammation of bursae and tendon sheaths is a key finding in PMR. Glucocorticoids have remained… read more here.
Keywords: synovial tissue; polymyalgia rheumatica; il6; expression ... See more keywords
Recurrent chromosomal rearrangements of ROS1, FRK and IL6 activating JAK/STAT pathway in inflammatory hepatocellular adenomas
Sign Up to like & getrecommendations! Published in 2020 at "Gut"
DOI: 10.1136/gutjnl-2019-319790
Abstract: Background Inflammatory hepatocellular adenomas (IHCAs) are benign liver tumours characterised by an activation of the janus kinase (JAK)/signal transducers and activators of transcription (STAT) pathway caused by oncogenic activating mutations. However, a subset of IHCA… read more here.
Keywords: stat pathway; il6; frk il6; ros1 frk ... See more keywords