Therapeutic potential of IL6R blockade for the treatment of sepsis and sepsis-related death: A Mendelian randomisation study
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DOI: 10.1371/journal.pmed.1004174
Abstract: Background Sepsis is characterised by dysregulated, life-threatening immune responses, which are thought to be driven by cytokines such as interleukin 6 (IL-6). Genetic variants in IL6R known to down-regulate IL-6 signalling are associated with improved… read more here.
Keywords: sepsis; effect; il6r blockade; critical care ... See more keywords