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Published in 2023 at "Advanced Science"
DOI: 10.1002/advs.202206958
Abstract: Development of abdominal aortic aneurysms (AAA) enhances lesion group‐2 innate lymphoid cell (ILC2) accumulation and blood IL5. ILC2 deficiency in Rorafl/flIl7rCre/+ mice or induced ILC2 depletion in Icosfl‐DTR‐fl/+Cd4Cre/+ mice expedites AAA growth, increases lesion inflammation,…
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Keywords:
il5;
ilc2;
via il5;
abdominal aortic ... See more keywords
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Published in 2017 at "European Journal of Immunology"
DOI: 10.1002/eji.201746961
Abstract: Recent studies identified an emerging role of group 2 and 3 innate lymphoid cells (ILCs) as key players in the generation of T‐dependent and T‐independent antibody production. In this retrospective case‐control study, CD117+ ILCs (including…
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Keywords:
ilc2;
reduction;
patients common;
group innate ... See more keywords
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1
Published in 2022 at "Cardiovascular Research"
DOI: 10.1093/cvr/cvac144
Abstract: Abstract Aims Group 2 innate lymphoid cells (ILC2s) regulate adaptive and innate immunities. In mouse heart, production of myocardial infarction (MI) increased ILC2 accumulation, suggesting a role for ILC2 in cardiac dysfunction post-MI. Methods and…
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Keywords:
il5;
ilc2;
group innate;
mice ... See more keywords
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0
Published in 2021 at "Respiratory Research"
DOI: 10.1186/s12931-021-01852-3
Abstract: Background Prostaglandin D 2 (PGD 2 ) signaling via prostaglandin D 2 receptor 2 (DP 2 ) contributes to atopic and non-atopic asthma. Inhibiting DP 2 has shown therapeutic benefit in certain subsets of asthma…
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Keywords:
ilc2;
prostaglandin;
cytokine secretion;
pgd ... See more keywords
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Published in 2017 at "PLoS ONE"
DOI: 10.1371/journal.pone.0188649
Abstract: Introduction Innate lymphoid cells (ILC) have been implicated in the initiation of inflammation and fibrosis in mice. However, ILC have not been characterized in inflamed human liver tissue. Methods Human intrahepatic lymphocytes were isolated by…
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Keywords:
ilc2;
liver disease;
human intrahepatic;
intrahepatic ilc2 ... See more keywords
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1
Published in 2021 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2021.688647
Abstract: Innate lymphoid cells (ILCs) are a recently discovered lymphocyte population with high cytokine productive capacity. Type-2 ILCs (ILC2s) are the most studied, and they exert a rapid type-2 immune response to eliminate helminth infections. Massive…
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Keywords:
ilc2;
various kidney;
fibrosis;
inflammation ... See more keywords