P071 Crohn’s Disease is associated with elevated levels of the pro-inflammatory CXCR3 ligands (CXCL9, 10 and 11) with an associated reduction in Paneth cell derived antimicrobial peptides in ex-vivo ileal biopsies
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DOI: 10.1093/ecco-jcc/jjab076.200
Abstract: Despite an expanding array of treatment options, a significant proportion of patients with Crohn’s Disease (CD) fail to respond to currently available therapies, underpinning the importance of biological insights into disease pathogenesis. The pro-inflammatory chemokines… read more here.
Keywords: pro inflammatory; paneth; ileal biopsies; paneth cell ... See more keywords