Abstract 3080: ILEI regulates LIFR expression and CSC self-renewal
Sign Up to like & getrecommendations! Published in 2021 at "Tumor Biology"
DOI: 10.1158/1538-7445.am2021-3080
Abstract: Our lab has previously identified a mechanism of transforming growth factor beta (TGFβ)-mediated epithelial-to-mesenchymal transition (EMT) in normal murine mammary gland (NMuMG) cells. Reduced expression of heterogenous nuclear ribonucleoprotein E1 (hnRNP E1, hereafter “E1”) in… read more here.
Keywords: expression; ilei; spheroid formation; ilei lifr ... See more keywords
FAM3C/ILEI protein is elevated in psoriatic lesions and triggers psoriasiform hyperproliferation in mice.
Sign Up to like & getrecommendations! Published in 2023 at "EMBO molecular medicine"
DOI: 10.15252/emmm.202216758
Abstract: FAM3C/ILEI is an important cytokine for tumor progression and metastasis. However, its involvement in inflammation remains elusive. Here, we show that ILEI protein is highly expressed in psoriatic lesions. Inducible keratinocyte-specific ILEI overexpression in mice… read more here.
Keywords: fam3c ilei; psoriatic lesions; mice; ilei protein ... See more keywords