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Published in 2021 at "Biophysical journal"
DOI: 10.1016/j.bpj.2021.01.040
Abstract: Beyond the critical role of cell nuclei in gene expression and DNA replication, they also have a significant influence on cell mechanosensation and migration. Nuclear stiffness can impact force transmission and, further, act as a…
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Keywords:
image derived;
stiffness;
derived modeling;
strain amplification ... See more keywords
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Published in 2021 at "NeuroImage"
DOI: 10.1016/j.neuroimage.2021.117950
Abstract: In present study we aimed to validate the use of image-derived input functions (IDIF) in the kinetic modeling of cerebral blood flow (CBF) measured by [15O]H2O PET by comparing with the accepted reference standard arterial…
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Keywords:
kinetic modeling;
pet;
image derived;
derived input ... See more keywords
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Published in 2022 at "IEEE Journal of Biomedical and Health Informatics"
DOI: 10.1109/jbhi.2022.3193190
Abstract: The non-invasive quantification of the cerebral metabolic rate for glucose (CMRGlc) and the characterization of cerebral metabolism in the cerebrovascular territories are helpful in understanding ischemic cerebrovascular disease (ICVD). Firstly, we investigated a non-invasive quantification…
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Keywords:
image derived;
metabolism;
quantification;
non invasive ... See more keywords
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Published in 2022 at "Stroke"
DOI: 10.1161/svin.122.000426
Abstract: Background While image-derived predictors of intracranial aneurysm (IA) rupture have been well-explored, current understanding of IA growth is limited. Pulsatility index (PI) and wall shear stress pulsatility index (WSSPI) are important metrics measuring temporal hemodynamic…
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Keywords:
growth;
image derived;
hemodynamic instability;
derived metrics ... See more keywords
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Published in 2018 at "EJNMMI Research"
DOI: 10.1186/s13550-018-0412-6
Abstract: BackgroundKinetic analysis of dynamic PET data requires an accurate knowledge of available PET tracer concentration within blood plasma over time, known as the arterial input function (AIF). The gold standard method used to measure the…
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Keywords:
image derived;
simultaneous estimation;
method;
estimation method ... See more keywords
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Published in 2022 at "PLOS ONE"
DOI: 10.1371/journal.pone.0277344
Abstract: Recent evidence suggests that shorter telomere length (TL) is associated with neuro degenerative diseases and aging related outcomes. The causal association between TL and brain characteristics represented by image derived phenotypes (IDPs) from different magnetic…
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Keywords:
image derived;
telomere length;
mendelian randomization;
brain ... See more keywords
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Published in 2023 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2023.1074052
Abstract: Introduction: Dynamic positron emission tomography (PET) and the application of kinetic models can provide important quantitative information based on its temporal information. This however requires arterial blood sampling, which can be challenging to acquire. Nowadays,…
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Keywords:
blood sampling;
image derived;
whole body;
input functions ... See more keywords