Lessons learned in application driven imaging agent design for image-guided surgery
Sign Up to like & getrecommendations! Published in 2024 at "European Journal of Nuclear Medicine and Molecular Imaging"
DOI: 10.1007/s00259-024-06791-x
Abstract: To meet the growing demand for intraoperative molecular imaging, the development of compatible imaging agents plays a crucial role. Given the unique requirements of surgical applications compared to diagnostics and therapy, maximizing translational potential necessitates… read more here.
Keywords: agent; imaging agent; molecular imaging; lessons learned ... See more keywords
Development of a Novel Imaging Agent for Determining Albumin Uptake in Solid Tumors
Sign Up to like & getrecommendations! Published in 2019 at "Nuclear Medicine and Molecular Imaging"
DOI: 10.1007/s13139-019-00587-w
Abstract: PurposeThe purpose of this study was to investigate the albumin-binding compound 111In-C4-DTPA as an imaging agent for the detection of endogenous albumin accumulation in tumors.Methods111In-C4-DTPA was injected in healthy nude mice for pharmacokinetic and biodistribution… read more here.
Keywords: post injection; dtpa; novel imaging; imaging agent ... See more keywords
A Dual-Mode Near-Infrared Optical and Photoacoustic Imaging Agent Based on a Low Energy Absorbing Ytterbium Complex.
Sign Up to like & getrecommendations! Published in 2024 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.4c03406
Abstract: Near-infrared (NIR) luminescence and photoacoustic (PA) imaging have attracted increasing attention for the real-time monitoring of biological samples due to high sensitivity, resolution, and pronounced signal detection depth, respectively. For improved contrast, both techniques require… read more here.
Keywords: dual mode; photoacoustic imaging; ytterbium; imaging agent ... See more keywords
Intraoperative ureter visualization using a near-infrared imaging agent
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Biomedical Optics"
DOI: 10.1117/1.jbo.24.6.066004
Abstract: Abstract. The fluorescent imaging agent IS-001 was determined to be well tolerated in all subjects and has the potential to provide ureter visualization throughout minimally invasive hysterectomy procedures. This study was conducted to evaluate clinical… read more here.
Keywords: near infrared; visualization using; ureter visualization; imaging agent ... See more keywords
Synthesis, docking, and preliminary in vitro/in vivo evaluation of MPP-dithiocarbamate-capped silver nanoparticle as dual-imaging agent for 5HT1A
Sign Up to like & getrecommendations! Published in 2018 at "International Journal of Nanomedicine"
DOI: 10.2147/ijn.s125009
Abstract: Methoxyphenyl piperazine is a versatile pharmacophore and has been exploited for targeting 5HT1A receptors. In the present study, silver nanoparticles were conjugated (capped) with methoxyphenyl piperazine-dithiocarbamate for application as targeted optical imaging agent at extremely… read more here.
Keywords: dithiocarbamate; imaging agent; synthesis; methoxyphenyl piperazine ... See more keywords
Noninvasive evaluation of the migration effect of transplanted endothelial progenitor cells in ischemic muscle using a multimodal imaging agent
Sign Up to like & getrecommendations! Published in 2018 at "International Journal of Nanomedicine"
DOI: 10.2147/ijn.s152976
Abstract: Background Endothelial progenitor cells (EPCs) play an important role in repairing ischemia tissues. However, the survival, migration and therapeutic efficacy of EPCs after transplantation need to be better understood for further cell therapy. Purpose This… read more here.
Keywords: optical imaging; multimodal imaging; migration; imaging ... See more keywords
[124I]IBETA: A New Aβ Plaque Positron Emission Tomography Imaging Agent for Alzheimer’s Disease
Sign Up to like & getrecommendations! Published in 2022 at "Molecules"
DOI: 10.3390/molecules27144552
Abstract: Several fluorine-18-labeled PET β-amyloid (Aβ) plaque radiotracers for Alzheimer’s disease (AD) are in clinical use. However, no radioiodinated imaging agent for Aβ plaques has been successfully moved forward for either single-photon emission computed tomography (SPECT)… read more here.
Keywords: imaging agent; plaque; 125i ibeta; fad mouse ... See more keywords