Imaging of atherosclerosis, targeting LFA-1 on inflammatory cells with 111In-DANBIRT
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Nuclear Cardiology"
DOI: 10.1007/s12350-018-1244-5
Abstract: Background111In-DOTA-butylamino-NorBIRT (DANBIRT) is a novel radioligand which binds to Leukocyte Function-associated Antigen-1 (LFA-1), expressed on inflammatory cells. This study evaluated 111In-DANBIRT for the visualization of atherosclerotic plaque inflammation in mice.Methods and ResultsApoE−/− mice, fed an… read more here.
Keywords: inflammatory cells; danbirt; danbirt uptake; imaging atherosclerosis ... See more keywords
Targeted Imaging in Atherosclerosis.
Sign Up to like & getrecommendations! Published in 2022 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.2c02644
Abstract: Atherosclerosis is a chronic inflammatory disease involved in plaque rupture, stroke, thrombosis, and heart attack (myocardial infarction), which is a leading cause of sudden cardiovascular events. In the past decades, various imaging strategies have been… read more here.
Keywords: atherosclerosis targeted; targeted imaging; imaging atherosclerosis; chemistry ... See more keywords
Quinazoline-2-Carboxamides as Selective PET Radiotracers for Matrix Metalloproteinase-13 Imaging in Atherosclerosis.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of medicinal chemistry"
DOI: 10.1021/acs.jmedchem.2c02107
Abstract: Matrix metalloproteinase-13 (MMP-13) plays a critical role in the progression of unstable atherosclerosis. A series of highly potent and selective MMP-13 inhibitors were synthesized around a quinazoline-2-carboxamide scaffold to facilitate radiolabeling with fluorine-18 or carbon-11… read more here.
Keywords: matrix metalloproteinase; imaging atherosclerosis; atherosclerosis; quinazoline carboxamides ... See more keywords
Erratum to “Magnetic Resonance Imaging of Atherosclerosis Using CD81-Targeted Microparticles of Iron Oxide in Mice”
Sign Up to like & getrecommendations! Published in 2018 at "BioMed Research International"
DOI: 10.1155/2018/8093438
Abstract: [This corrects the article DOI: 10.1155/2015/758616.]. read more here.
Keywords: using cd81; resonance imaging; atherosclerosis using; magnetic resonance ... See more keywords
Intravascular Imaging of Atherosclerosis by Using Engineered Nanoparticles
Sign Up to like & getrecommendations! Published in 2023 at "Biosensors"
DOI: 10.3390/bios13030319
Abstract: Atherosclerosis is a leading cause of morbidity and mortality, and high-risk atherosclerotic plaques can result in myocardial infarction, stroke, and/or sudden death. Various imaging and sensing techniques (e.g., ultrasound, optical coherence tomography, fluorescence, photoacoustic) have… read more here.
Keywords: intravascular imaging; imaging atherosclerosis; high risk; atherosclerosis using ... See more keywords
Small Dimension–Big Impact! Nanoparticle-Enhanced Non-Invasive and Intravascular Molecular Imaging of Atherosclerosis In Vivo
Sign Up to like & getrecommendations! Published in 2020 at "Molecules"
DOI: 10.3390/molecules25051029
Abstract: Extensive translational research has provided considerable progress regarding the understanding of atherosclerosis pathophysiology over the last decades. In contrast, implementation of molecular in vivo imaging remains highly limited. In that context, nanoparticles represent a useful… read more here.
Keywords: small dimension; big impact; imaging atherosclerosis; molecular imaging ... See more keywords