Imaging depth variations in hyperspectral imaging: development of a method to detect tumor up to the required tumor-free margin width.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of biophotonics"
DOI: 10.1002/jbio.201900086
Abstract: Hyperspectral imaging is a promising technique for resection margin assessment during cancer surgery. Thereby, only a specific amount of the tissue below the resection surface, the clinically defined margin width, should be assessed. Since the… read more here.
Keywords: imaging depth; hyperspectral imaging; method; margin width ... See more keywords
Comparing Imaging Depth of Intravital Lung Imaging Using Perfluorocarbon-Based Liquid Ventilation With Tissue Clearing for Deep-Tissue Imaging.
Sign Up to like & getrecommendations! Published in 2025 at "Journal of biophotonics"
DOI: 10.1002/jbio.202500145
Abstract: ABSTRACT Intravital lung imaging has been employed to study physiological and pathophysiological processes related to nanoparticle deposition in the alveolar lung, particularly in the context of air pollution and drug delivery. However, optical imaging depth… read more here.
Keywords: liquid ventilation; imaging depth; tissue; intravital lung ... See more keywords
A novel method (RIM-Deep) for enhancing imaging depth and resolution stability of deep cleared tissue in inverted confocal microscopy
Sign Up to like & getrecommendations! Published in 2025 at "eLife"
DOI: 10.1101/2024.07.19.604108
Abstract: The increasing use of tissue clearing techniques underscores the urgent need for cost-effective and simplified deep imaging methods. While traditional inverted confocal microscopes excel in high-resolution imaging of tissue sections and cultured cells, they face… read more here.
Keywords: rim deep; imaging depth; inverted confocal; deep imaging ... See more keywords
Aberration correction in stimulated emission depletion microscopy to increase imaging depth in living brain tissue
Sign Up to like & getrecommendations! Published in 2021 at "Neurophotonics"
DOI: 10.1117/1.nph.8.3.035001
Abstract: Abstract. Significance: Stimulated emission depletion (STED) microscopy enables nanoscale imaging of live samples, but it requires a specific spatial beam shaping that is highly sensitive to optical aberrations, limiting its depth penetration. Therefore, there is… read more here.
Keywords: imaging depth; microscopy; correction; living brain ... See more keywords
Tissue imaging depth limit of stimulated Raman scattering microscopy.
Sign Up to like & getrecommendations! Published in 2020 at "Biomedical optics express"
DOI: 10.1364/boe.382396
Abstract: Stimulated Raman scattering (SRS) microscopy is a promising technique for studying tissue structure, physiology, and function. Similar to other nonlinear optical imaging techniques, SRS is severely limited in imaging depth due to the turbidity and… read more here.
Keywords: raman scattering; imaging depth; microscopy; tissue imaging ... See more keywords
Rigorous modelling of second harmonic generation imaging through stratified media focused by radially polarized beams.
Sign Up to like & getrecommendations! Published in 2019 at "Optics express"
DOI: 10.1364/oe.27.019737
Abstract: For second harmonic generation (SHG) imaging, the specimen is often observed through an immersion medium and a cover glass whose refractive indices are usually different from that of the specimen. However, the currently used theoretical… read more here.
Keywords: imaging depth; harmonic generation; shg imaging; stratified media ... See more keywords
On the imaging depth limit of photoacoustic tomography in the visible and first near-infrared windows.
Sign Up to like & getrecommendations! Published in 2024 at "Optics express"
DOI: 10.1364/oe.513538
Abstract: It is well known that photoacoustic tomography (PAT) can circumvent the photon scattering problem in optical imaging and achieve high-contrast and high-resolution imaging at centimeter depths. However, after two decades of development, the long-standing question… read more here.
Keywords: visible first; depth limit; imaging depth; photoacoustic tomography ... See more keywords
Multi-channel delay sampling to extend imaging depth in high-speed swept-source OCT systems.
Sign Up to like & getrecommendations! Published in 2024 at "Optics letters"
DOI: 10.1364/ol.517493
Abstract: We present a multi-channel delay sampling method to extend imaging depth in high-speed swept-source optical coherence tomography (SS-OCT). A balanced detector captures interference signals, converting them into electrical signals, which are then split into N… read more here.
Keywords: extend imaging; imaging depth; delay sampling; multi channel ... See more keywords