Imaging Glioma Progression by Intravital Microscopy.
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DOI: 10.1007/978-1-4939-8769-6_16
Abstract: We describe here a method for generating mouse orthotopic gliomas in order to follow their progression over time by multi-photon laser scanning microscopy. After craniotomy of the parietal bone, glioma cells are implanted in the… read more here.
Keywords: microscopy; intravital microscopy; progression intravital; glioma progression ... See more keywords
Targeting MMP-14 for dual PET and fluorescence imaging of glioma in preclinical models
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DOI: 10.1007/s00259-019-04607-x
Abstract: Purpose There is a clinical need for agents that target glioma cells for non-invasive and intraoperative imaging to guide therapeutic intervention and improve the prognosis of glioma. Matrix metalloproteinase (MMP)-14 is overexpressed in glioma with… read more here.
Keywords: binding peptide; substrate binding; imaging glioma; glioma ... See more keywords
Imaging glioma biology: spatial comparison of amino acid PET, amide proton transfer, and perfusion-weighted MRI in newly diagnosed gliomas
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DOI: 10.1007/s00259-019-04677-x
Abstract: Purpose Imaging glioma biology holds great promise to unravel the complex nature of these tumors. Besides well-established imaging techniques such O-(2-[18F]fluoroethyl)- l -tyrosine (FET)-PET and dynamic susceptibility contrast (DSC) perfusion imaging, amide proton transfer–weighted (APTw)… read more here.
Keywords: gliomas; glioma biology; amide proton; biology ... See more keywords
Imaging of the glioma microenvironment by TSPO PET
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DOI: 10.1007/s00259-021-05276-5
Abstract: Gliomas are highly dynamic and heterogeneous tumours of the central nervous system (CNS). They constitute the most common neoplasm of the CNS and the second most common cause of death from intracranial disease after stroke.… read more here.
Keywords: pet; tspo pet; pet imaging; imaging glioma ... See more keywords