Cancer cell identification by facile imaging of intracellular reductive substances with fluorescent nanosensor.
Sign Up to like & getrecommendations! Published in 2021 at "Talanta"
DOI: 10.1016/j.talanta.2021.122650
Abstract: Ascorbic acid (AA) and glutathione (GSH), the most abundant intracellular reductive substances, have been widely used as biomarkers for cancer cells identification. The current methods relying on imaging of AA or GSH alone to identify… read more here.
Keywords: intracellular reductive; reductive substances; cancer cells; cancer ... See more keywords
Quantitative imaging of intracellular nanoparticle exposure enables prediction of nanotherapeutic efficacy
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DOI: 10.1038/s41467-021-22678-z
Abstract: Nanoparticle internalisation is crucial for the precise delivery of drug/genes to its intracellular targets. Conventional quantification strategies can provide the overall profiling of nanoparticle biodistribution, but fail to unambiguously differentiate the intracellularly bioavailable particles from… read more here.
Keywords: nanoparticle; quantitative imaging; nanoparticle exposure; intracellular nanoparticle ... See more keywords
Computational Modeling and Imaging of the Intracellular Oxygen Gradient
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DOI: 10.3390/ijms232012597
Abstract: Computational modeling can provide a mechanistic and quantitative framework for describing intracellular spatial heterogeneity of solutes such as oxygen partial pressure (pO2). This study develops and evaluates a finite-element model of oxygen-consuming mitochondrial bioenergetics using… read more here.
Keywords: modeling imaging; po2; computational modeling; model ... See more keywords