Oncolytic Viruses for Tumor Precision Imaging and Radiotherapy.
Sign Up to like & getrecommendations! Published in 2018 at "Human gene therapy"
DOI: 10.1089/hum.2017.189
Abstract: In 2003 in China, Peng et al. invented the recombinant adenovirus expressing p53 (Gendicine) for clinical tumor virotherapy. This was the first clinically approved gene therapy and tumor virotherapy drug in the world. An oncolytic… read more here.
Keywords: tumor precision; imaging radiotherapy; oncolytic viruses;
Phenylboronic acid conjugated multifunctional nanogels with 131I-labeling for targeted SPECT imaging and radiotherapy of breast adenocarcinoma
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Bioengineering and Biotechnology"
DOI: 10.3389/fbioe.2022.973141
Abstract: We report a new 131I-labeling functional platform for targeted single-photon emission computed tomography (SPECT) imaging and radiotherapy of breast adenocarcinoma. In this study, polyethyleneimine (PEI) based nanogels (P.NH2 NGs) were prepared by water/oil polymerization, modified… read more here.
Keywords: breast adenocarcinoma; 131i labeling; spect imaging; imaging radiotherapy ... See more keywords
DNA Repair Enzyme Poly(ADP-Ribose) Polymerase 1/2 (PARP1/2)-Targeted Nuclear Imaging and Radiotherapy
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DOI: 10.3390/cancers14051129
Abstract: Simple Summary In parallel to the successful clinical implementation of PARP1/2 inhibitors as anti-cancer drugs, which interfere with the DNA repair machinery, these small molecule agents have also gained attention as vehicles for molecular imaging… read more here.
Keywords: dna repair; imaging radiotherapy; radiotherapy; parp targeted ... See more keywords
Recent Advances in 64Cu/67Cu-Based Radiopharmaceuticals
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DOI: 10.3390/ijms24119154
Abstract: Copper-64 (T1/2 = 12.7 h) is a positron and beta-emitting isotope, with decay characteristics suitable for both positron emission tomography (PET) imaging and radiotherapy of cancer. Copper-67 (T1/2 = 61.8 h) is a beta and… read more here.
Keywords: copper; imaging radiotherapy; based radiopharmaceuticals; 64cu 67cu ... See more keywords