Imatinib has minimal effects on inflammatory and osteopenic phenotypes in a murine cherubism model.
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DOI: 10.1111/odi.14073
Abstract: OBJECTIVE Cherubism is a genetic disorder characterised by bilateral jawbone deformation. The associated jawbone lesions regress after puberty, whereas severe cases require surgical treatment. Although several drugs have been tested, fundamental treatment strategies for cherubism… read more here.
Keywords: imatinib minimal; cherubism mutant; cherubism; model ... See more keywords