The multi-decadal morphodynamic changes of the mouth bar in a mixed fluvial-tidal estuarine channel
Sign Up to like & getrecommendations! Published in 2020 at "Marine Geology"
DOI: 10.1016/j.margeo.2020.106311
Abstract: Abstract Inner-channel mouth bars (IMB) are common and vital geomorphological structures in estuaries that can efficiently promote the progradation of a fluvial delta. However, these significant structures face serious interferences by natural and human forces.… read more here.
Keywords: mixed fluvial; imb; mouth bar; fluvial tidal ... See more keywords
A novel protein kinase inhibitor IMB-YH-8 with anti-tuberculosis activity
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-04108-7
Abstract: Protein kinase B (PknB) is one of the Mycobacterium tuberculosis serine/threonine protein kinases and has an essential role in sustaining mycobacterial growth. Here, we identified and characterized a novel small molecule compound named IMB-YH-8 that… read more here.
Keywords: inhibitor; imb; tuberculosis; protein kinase ... See more keywords
IMB-T130 targets 3-dehydroquinate synthase and inhibits Mycobacterium tuberculosis
Sign Up to like & getrecommendations! Published in 2018 at "Scientific Reports"
DOI: 10.1038/s41598-018-35701-z
Abstract: The anti-tuberculosis (TB) agent IMB-T130 was speculated to be a multi-target compound. In this research, we found that IMB-T130 inhibits the catalytic activity of Mycobacterium tuberculosis 3-dehydroquinate synthase (MtDHQS), the enzyme in the second step… read more here.
Keywords: dehydroquinate synthase; imb; imb t130; mycobacterium tuberculosis ... See more keywords
Sevoflurane Preconditioning Increases Stress Resistance via IMB-2/DAF-16 in Caenorhabditis Elegans
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DOI: 10.1177/15593258221082886
Abstract: Sevoflurane preconditioning has been proved to possess therapeutic effects on stress. However, the mechanism by which sevoflurane preconditioning protects against stress remains unclear. In this study, an acute model of heat stress in C.eleans was… read more here.
Keywords: imb; daf; stress resistance; sevoflurane ... See more keywords
Bioactive nutraceuticals oligo-lactic acid and fermented soy extract alleviate cognitive decline in mice in part via anti-neuroinflammation and modulation of gut microbiota
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Nutrition"
DOI: 10.3389/fnut.2023.1116278
Abstract: Introduction Cognition decline is associated with aging and certain diseases, such as neurodegenerative or neuropsychiatric disorders, diabetes and chronic kidney disease. Inflammation/neuroinflammation is considered an important causal factor, and experimental evidence suggests that anti-inflammatory natural… read more here.
Keywords: decline; cognition; gut microbiota; neuroinflammation ... See more keywords