Elevated serum interferon γ-induced protein 10 kDa is associated with TAFRO syndrome
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/srep42316
Abstract: Multicentric Castleman disease (MCD) is a heterogeneous lymphoproliferative disorder. It is characterized by inflammatory symptoms, and interleukin (IL)-6 contributes to the disease pathogenesis. Human herpesvirus 8 (HHV-8) often drives hypercytokinemia in MCD, although the etiology… read more here.
Keywords: imcd; interferon induced; induced protein; tafro imcd ... See more keywords
Natural History Study of Idiopathic Multicentric Castleman Disease Identifies Effective Treatments for a Large Proportion of Patients but Treatment-Refractory Patients Remain
Sign Up to like & getrecommendations! Published in 2019 at "Blood"
DOI: 10.1182/blood-2019-131367
Abstract: Background Human herpes-virus 8-negative/idiopathic multicentric Castleman disease (iMCD) is a rare inflammatory disorder involving multicentric lymphadenopathy with characteristic histopathology. Clinical presentation is heterogenous and includes cytokine-driven constitutional symptoms, cytopenias, systemic inflammation, and multi-organ dysfunction. International… read more here.
Keywords: imcd; response; treatment; castleman disease ... See more keywords
Overview of Castleman Disease.
Sign Up to like & getrecommendations! Published in 2020 at "Blood"
DOI: 10.1182/blood.2019000931
Abstract: Castleman disease (CD) describes a group of at least four disorders that share a spectrum of characteristic histopathological features but have a wide range of etiologies, presentations, treatments, and outcomes. CD includes unicentric CD (UCD)… read more here.
Keywords: imcd; disease; castleman disease; overview castleman ... See more keywords
Idiopathic multicentric Castleman disease with pulmonary and cutaneous lesions treated with tocilizumab: A case report
Sign Up to like & getrecommendations! Published in 2020 at "World Journal of Clinical Cases"
DOI: 10.12998/wjcc.v8.i20.4922
Abstract: BACKGROUND Human herpes virus-8 (HHV-8)-negative, idiopathic multicentric Castleman disease (iMCD) is a rare and life-threatening disorder driven by proinflammatory cytokines, which is still poorly understood. Pulmonary parenchyma lesion is a rare condition in iMCD, which… read more here.
Keywords: imcd; multicentric castleman; castleman disease; idiopathic multicentric ... See more keywords