Small RNA‐Seq analysis reveals microRNA‐regulation of the Imd pathway during Escherichia coli infection in Drosophila
Sign Up to like & getrecommendations! Published in 2017 at "Developmental and Comparative Immunology"
DOI: 10.1016/j.dci.2017.01.008
Abstract: ABSTRACT Drosophila have served as a model for research on innate immunity for decades. However, knowledge of the post‐transcriptional regulation of immune gene expression by microRNAs (miRNAs) remains rudimentary. In the present study, using small… read more here.
Keywords: drosophila; small rna; imd pathway; analysis ... See more keywords
Croquemort elicits activation of the immune deficiency pathway in ticks.
Sign Up to like & getrecommendations! Published in 2023 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2208673120
Abstract: The immune deficiency (IMD) pathway directs host defense in arthropods upon bacterial infection. In Pancrustacea, peptidoglycan recognition proteins sense microbial moieties and initiate nuclear factor-κB-driven immune responses. Proteins that elicit the IMD pathway in non-insect… read more here.
Keywords: pathway; elicits activation; croquemort elicits; immune deficiency ... See more keywords
The Unfolded-Protein Response Triggers the Arthropod Immune Deficiency Pathway
Sign Up to like & getrecommendations! Published in 2022 at "mBio"
DOI: 10.1128/mbio.00703-22
Abstract: The ability of an arthropod to harbor and transmit pathogens is termed “vector competency.” Many factors influence vector competency, including how arthropod immune processes respond to the microbe. Divergences in innate immunity between arthropods are… read more here.
Keywords: response; arthropod immune; vector competency; imd pathway ... See more keywords
Rhodnius prolixus: Identification of missing components of the IMD immune signaling pathway and functional characterization of its role in eliminating bacteria
Sign Up to like & getrecommendations! Published in 2019 at "PLoS ONE"
DOI: 10.1371/journal.pone.0214794
Abstract: The innate immune system in insects is regulated by specific signalling pathways. Most immune related pathways were identified and characterized in holometabolous insects such as Drosophila melanogaster, and it was assumed they would be highly… read more here.
Keywords: insects; prolixus identification; imd pathway; rhodnius prolixus ... See more keywords
Identification and Analysis of a Gene with Potential to Repress the IMD Pathway in Drosophila melanogaster
Sign Up to like & getrecommendations! Published in 2019 at "Zoological Science"
DOI: 10.2108/zs190003
Abstract: The IMD pathway is one of the signal transduction pathways that regulates innate immune responses in Drosophila. To understand the regulation mechanism of the IMD pathway, we performed a mis-expression screening and identified a gene,… read more here.
Keywords: gene potential; imd pathway; identification analysis; analysis gene ... See more keywords
Dynamic Regulation of NF-κB Response in Innate Immunity: The Case of the IMD Pathway in Drosophila
Sign Up to like & getrecommendations! Published in 2022 at "Biomedicines"
DOI: 10.3390/biomedicines10092304
Abstract: Metazoans have developed strategies to protect themselves from pathogenic attack. These preserved mechanisms constitute the immune system, composed of innate and adaptive responses. Among the two kinds, the innate immune system involves the activation of… read more here.
Keywords: response; dynamic regulation; immune response; regulation ... See more keywords
Identification of the Gene Repertoire of the IMD Pathway and Expression of Antimicrobial Peptide Genes in Several Tissues and Hemolymph of the Cockroach Blattella germanica
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23158444
Abstract: Antimicrobial peptide (AMP) genes, triggered by Toll and IMD pathways, are essential components of the innate immune system in the German cockroach Blattella germanica. Besides their role in killing pathogenic bacteria, AMPs could be involved… read more here.
Keywords: cockroach blattella; blattella germanica; antimicrobial peptide; expression ... See more keywords