Effectiveness of Casirivimab-Imdevimab and Sotrovimab During a SARS-CoV-2 Delta Variant Surge: A Cohort Study and Randomized Comparative Effectiveness Trial.
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DOI: 10.1001/jamanetworkopen.2022.20957
Abstract: Importance The effectiveness of monoclonal antibodies (mAbs), casirivimab-imdevimab and sotrovimab, is unknown in patients with mild to moderate COVID-19 caused by the SARS-CoV-2 Delta variant. Objective To evaluate the effectiveness of mAb against the Delta… read more here.
Keywords: casirivimab imdevimab; imdevimab; effectiveness; mab treatment ... See more keywords
Virologic Efficacy of Casirivimab and Imdevimab COVID-19 Antibody Combination in Outpatients With SARS-CoV-2 Infection
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DOI: 10.1001/jamanetworkopen.2022.25411
Abstract: Key Points Question Can casirivimab and imdevimab effectively reduce the viral load of SARS-CoV-2 with lower doses and a subcutaneous route of administration? Findings In this phase 2 randomized clinical trial of outpatients with SARS-CoV-2,… read more here.
Keywords: administration; outpatients sars; casirivimab imdevimab; imdevimab ... See more keywords
Casirivimab/Imdevimab: First Approval
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DOI: 10.1007/s40265-021-01620-z
Abstract: Casirivimab/imdevimab (Ronapreve™; REGEN-COV™) is a co-packaged combination of two neutralizing immunoglobulin gamma 1 (IgG1) human monoclonal antibodies (casirivimab and imdevimab) against the spike protein of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative… read more here.
Keywords: imdevimab; treatment; covid; casirivimab imdevimab ... See more keywords