Synthesis and Anti-Mycobacterium tuberculosis Activity of Imidazo[2,1-b][1,3]oxazine Derivatives Against Multidrug-Resistant Strains.
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DOI: 10.1002/cmdc.202300015
Abstract: The emergence of multidrug-resistant strains of M. tuberculosis has raised concerns due to the greater difficulties in patient treatment and higher mortality rates. Herein, we revisited the 2-nitro-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazine scaffold and identified potent new carbamate derivatives… read more here.
Keywords: imidazo oxazine; oxazine derivatives; activity; multidrug resistant ... See more keywords