Design, synthesis, and anticancer activity of imidazo[2,1-b]oxazole-based RAF kinase inhibitors.
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DOI: 10.1016/j.bioorg.2019.103349
Abstract: In the present work, a novel series of B-RAF kinase inhibitors having imidazo[2,1-b]oxazole scaffold was designed and synthesized based on the structures of the well-known B-RAF inhibitors. The twenty two final compounds were tested over… read more here.
Keywords: kinase inhibitors; imidazo oxazole; raf; raf kinase ... See more keywords