Articles with "imidazo pyrimidine" as a keyword



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Synthesis of Substituted imidazo [1, 5-a] pyrimidine-2-(1H)-one Core Structure.

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Published in 2020 at "Current organic synthesis"

DOI: 10.2174/1389200220666191122103445

Abstract: BACKGROUND AND OBJECTIVE The objective of our work was to establish a facile and scalable synthesis of imidazopyridone for further use in medicinal chemistry applications. An easy synthesis of a core scaffold will enable the… read more here.

Keywords: pyrimidine one; chemistry; one core; imidazo pyrimidine ... See more keywords
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4-(Aryl)-Benzo[4,5]imidazo[1,2-a]pyrimidine-3-Carbonitrile-Based Fluorophores: Povarov Reaction-Based Synthesis, Photophysical Studies, and DFT Calculations

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Published in 2022 at "Molecules"

DOI: 10.3390/molecules27228029

Abstract: A series of novel 4-(aryl)-benzo[4,5]imidazo[1,2-a]pyrimidine-3-carbonitriles were obtained through the Povarov (aza-Diels–Alder) and oxidation reactions, starting from benzimidazole-2-arylimines. Based on the literature data and X-ray diffraction analysis, it was discovered that during the Povarov reaction, [1,3]… read more here.

Keywords: povarov reaction; spectroscopy; aryl benzo; benzo imidazo ... See more keywords
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Microwave assisted, sequential two-step, one-pot synthesis of novel imidazo[1,2-a]pyrimidine containing tri/tetrasubstituted imidazole derivatives

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Published in 2021 at "Turkish Journal of Chemistry"

DOI: 10.3906/kim-2009-40

Abstract: A series of novel imidazo[1,2- a ]pyrimidine containing tri/tetrasubstituted imidazole derivatives (1-10) has been synthesized via sequential two-step, one-pot, multicomponent reaction using imidazo[1,2- a ]pyrimidine-2-carbaldehyde, benzil, primary amines, and ammonium acetate catalyzed by p -toluenesulfonic… read more here.

Keywords: containing tri; pyrimidine containing; pyrimidine; tri tetrasubstituted ... See more keywords