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Published in 2019 at "Xenobiotica"
DOI: 10.1080/00498254.2019.1581960
Abstract: Abstract 1. The absorption, metabolism, and excretion of a single oral 450-mg dose of [14C]-(S)-6-(3-cyclopentyl-2-(4-trifluoromethyl)-1H-imidazol-1-yl)propanamido)nicotinic acid (PF-04991532), a hepatoselective glucokinase activator, was investigated in humans. Mass balance was achieved with ∼94.6% of the administered dose…
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Keywords:
trifluoromethyl imidazol;
imidazol propanamido;
cyclopentyl;
metabolism ... See more keywords