Design, synthesis, biological evaluation of 6-(2-amino-1H-benzo[d]imidazole-6-yl)quinazolin-4(3H)-one derivatives as novel anticancer agents with Aurora kinase inhibition.
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DOI: 10.1016/j.ejmech.2020.112108
Abstract: Aurora A kinase, a member of the Aurora kinase family, is frequently overexpressed in various human cancers. In addition, Overexpression of Aurora A kinase is associated with drug resistance and poor prognosis in many cancers… read more here.
Keywords: amino benzo; kinase; imidazole quinazolin; benzo imidazole ... See more keywords