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Investigations on Anticancer Potentials by DNA Binding and Cytotoxicity Studies for Newly Synthesized and Characterized Imidazolidine and Thiazolidine-Based Isatin Derivatives

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Published in 2022 at "Molecules"

DOI: 10.3390/molecules27020354

Abstract: Imidazolidine and thiazolidine-based isatin derivatives (IST-01–04) were synthesized, characterized, and tested for their interactions with ds-DNA. Theoretical and experimental findings showed good compatibility and indicated compound–DNA binding by mixed mode of interactions. The evaluated binding… read more here.

Keywords: cell; based isatin; dna binding; imidazolidine thiazolidine ... See more keywords