Molecular docking, modeling, semiempirical calculations studies and in vitro evaluation of new synthesized pyrimidin-imide derivatives
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Molecular Structure"
DOI: 10.1016/j.molstruc.2021.131548
Abstract: Abstract New pyrimidin-imide derivatives 2-7 were synthesized by a condensation reaction of 4,6-diphenylpyrimidin-2-amine 1 with different anhydrides. The synthesized compounds have been investigated and put under several studies suc as, in vitro and in silico… read more here.
Keywords: pyrimidin; pyrimidin imide; imide derivatives; synthesized pyrimidin ... See more keywords
Synthesis, evaluation, molecular dynamics simulation and targets identification of novel pyrazole-containing imide derivatives
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Biomolecular Structure and Dynamics"
DOI: 10.1080/07391102.2020.1745284
Abstract: Abstract A new series of novel pyrazole-containing imide derivatives were synthesized and evaluated for their anticancer activities against A-549, Bel7402, and HCT-8 cell lines. Among these compounds A2, A4, A11 and A14 possessed high inhibition… read more here.
Keywords: molecular dynamics; pyrazole containing; containing imide; imide derivatives ... See more keywords