Pd-catalyzed imine-directed intramolecular C N bond formation through C(sp3) H activation: An efficient approach to multisubstituted pyrroles
Sign Up to like & getrecommendations! Published in 2020 at "Tetrahedron Letters"
DOI: 10.1016/j.tetlet.2020.151887
Abstract: Abstract An atom-economic approach to synthesize 1,2,4-trisubstituted pyrroles through palladium-catalyzed imine-directed intramolecular C(sp3) H amination reaction has been developed. The imine group acts as a directing group as well as an intramolecular nucleophile for the… read more here.
Keywords: sp3; imine directed; approach; directed intramolecular ... See more keywords
Rh(I)-catalysed imine-directed C-H functionalization via the oxidative [3 + 2] cycloaddition of benzylamine derivatives with maleimides.
Sign Up to like & getrecommendations! Published in 2022 at "Chemical communications"
DOI: 10.1039/d1cc06622f
Abstract: The Rh(I)-catalysed imine-directed oxidative [3 + 2] cycloaddition of benzylamines with maleimides is reported. A wide range of both benzylamines and maleimides is applicable to the reaction. A one-pot three component strategy using benzylamines, 2-pyridinecarboxaldehyde,… read more here.
Keywords: oxidative cycloaddition; catalysed imine; directed functionalization; imine directed ... See more keywords
Pd-catalyzed imine-directed one-pot access to polysubstituted pyrroles via tandem triple isocyanide insertion/aza-Nazarov cyclization reactions
Sign Up to like & getrecommendations! Published in 2023 at "Organic Chemistry Frontiers"
DOI: 10.1039/d3qo00598d
Abstract: Herein, we report a novel one-pot method for synthesizing polysubstituted pyrrole derivatives via three-component reactions of alkenyl bromides, amines, and isocyanides. The conversion process is catalyzed by a Pd catalyst... read more here.
Keywords: catalyzed imine; imine directed; one pot; directed one ... See more keywords