Asymmetric Formal [3 + 2]-Cycloaddition of Azomethine Imines with Azlactones To Synthesize Bicyclic Pyrazolidinones.
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DOI: 10.1021/acs.orglett.7b02772
Abstract: An efficient enantioselective formal [3 + 2]-cycloaddition of azomethine imines with azlactones has been realized by using a chiral bifunctional bisguanidinium hemisalt as the catalyst. Optically active bicyclic pyrazolidinone compounds were generated under mild reaction… read more here.
Keywords: formal cycloaddition; imines azlactones; azomethine imines; cycloaddition azomethine ... See more keywords