Stable triterpenoid iminium salts and their activity as inhibitors of butyrylcholinesterase
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Molecular Structure"
DOI: 10.1016/j.molstruc.2021.131646
Abstract: Abstract Amides derived from platanic acid (30-nor-lupane skeleton) were converted in two steps into 21-aza-17,19-ethano-19-nor-urs-20-en-21-ium chlorides. These ursane-skeleton iminium salts are first in their class, and some of them proved as selective inhibitors of the… read more here.
Keywords: triterpenoid iminium; iminium; iminium salts; stable triterpenoid ... See more keywords
Computational Study of the Stability of Pyrrolidine-Derived Iminium Ions: Exchange Equilibria between Iminium Ions and Carbonyl Compounds
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DOI: 10.1021/acsomega.1c07020
Abstract: The tendency of carbonyl compounds to form iminium ions by reaction with pyrrolidine or chiral pyrrolidine derivatives (in other words, the relative stability to hydrolysis of these iminium ions) has been computationally examined, mainly using… read more here.
Keywords: iminium; exchange equilibria; equilibria iminium; iminium ions ... See more keywords
Base-promoted aerobic oxidation of N-alkyl iminium salts derived from isoquinolines and related heterocycles
Sign Up to like & getrecommendations! Published in 2020 at "Green Chemistry"
DOI: 10.1039/c9gc03629f
Abstract: Potassium tert-butoxide-promoted aerobic oxidation of N-alkyl iminium salts is reported. The reaction is atom-economical and environmentally friendly. Iminium salts derived from isoquinoline, quinoline, phenanthridine, phenanthroline, and phthalazine were successfully transformed into their corresponding unsaturated lactams… read more here.
Keywords: iminium; promoted aerobic; oxidation alkyl; iminium salts ... See more keywords
Towards depeptidized aminoboronic acid derivatives through the use of borylated iminium ions.
Sign Up to like & getrecommendations! Published in 2022 at "Chemical communications"
DOI: 10.1039/d2cc00659f
Abstract: Herein, we use α-boryl iminium intermediates to access progressively depeptidized branched β-aminoboronic acids that are functionalized with biologically relevant heterocycles. We investigate the interaction of these novel compounds with carbohydrates under physiological conditions and demonstrate… read more here.
Keywords: derivatives use; iminium; towards depeptidized; aminoboronic acid ... See more keywords
Crystal structure and Hirshfeld surface analysis of (E)-3-[(4-chlorobenzylidene)amino]-5-phenylthiazolidin-2-iminium bromide
Sign Up to like & getrecommendations! Published in 2019 at "Acta Crystallographica Section E: Crystallographic Communications"
DOI: 10.1107/s2056989019009885
Abstract: In the crystal of the title salt, the cations and anions are linked via N—H⋯Br hydrogen bonds. In the 1H NMR spectra of this compound, the NH iminium protons are observed at δ = 10.46… read more here.
Keywords: iminium; surface analysis; hirshfeld surface; analysis chlorobenzylidene ... See more keywords
Crystal structure and Hirshfeld surface analysis of (E)-3-(benzylideneamino)-5-phenylthiazolidin-2-iminium bromide
Sign Up to like & getrecommendations! Published in 2020 at "Acta Crystallographica Section E: Crystallographic Communications"
DOI: 10.1107/s2056989020001899
Abstract: In the crystal, the cations and anions of the title salt are linked via N—H⋯Br hydrogen bonds. In the 1H NMR spectra of this compound, the NH iminium protons were observed at δ 10.35 p.p.m.,… read more here.
Keywords: iminium; surface analysis; hirshfeld surface; structure hirshfeld ... See more keywords
Recent Advances in Catalytic and Technology-Driven Radical Addition to N,N-Disubstituted Iminium Species
Sign Up to like & getrecommendations! Published in 2023 at "Molecules"
DOI: 10.3390/molecules28031071
Abstract: Recently, radical chemistry has grown exponentially in the toolbox of organic synthetic chemists. Upon the (re)introduction of modern catalytic and technology-driven strategies, the implementation of highly reactive radical species is currently facilitated while expanding the… read more here.
Keywords: iminium; chemistry; catalytic technology; technology driven ... See more keywords