Synthesis of Novel Dihydropyridine‐Iminium Salts Containing a Selenazine Core
Sign Up to like & getrecommendations! Published in 2025 at "Asian Journal of Organic Chemistry"
DOI: 10.1002/ajoc.70141
Abstract: Functionalizing organic molecules with selenium‐containing fragments is a strategy to increase the biological properties of natural products and biomolecules. Therefore, in the present study, this strategy was followed to develop a new series in which… read more here.
Keywords: chemistry; synthesis novel; iminium; novel dihydropyridine ... See more keywords
Stable triterpenoid iminium salts and their activity as inhibitors of butyrylcholinesterase
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Molecular Structure"
DOI: 10.1016/j.molstruc.2021.131646
Abstract: Abstract Amides derived from platanic acid (30-nor-lupane skeleton) were converted in two steps into 21-aza-17,19-ethano-19-nor-urs-20-en-21-ium chlorides. These ursane-skeleton iminium salts are first in their class, and some of them proved as selective inhibitors of the… read more here.
Keywords: triterpenoid iminium; iminium; iminium salts; stable triterpenoid ... See more keywords
Computational Study of the Stability of Pyrrolidine-Derived Iminium Ions: Exchange Equilibria between Iminium Ions and Carbonyl Compounds
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DOI: 10.1021/acsomega.1c07020
Abstract: The tendency of carbonyl compounds to form iminium ions by reaction with pyrrolidine or chiral pyrrolidine derivatives (in other words, the relative stability to hydrolysis of these iminium ions) has been computationally examined, mainly using… read more here.
Keywords: iminium; exchange equilibria; equilibria iminium; iminium ions ... See more keywords
Organocatalytic iminium-assisted asymmetric B(sp²)-to-B(sp³) transformation
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DOI: 10.1038/s41467-025-65393-9
Abstract: Tetracoordinate boron compounds are widely used as dyes in medicinal research and material sciences. Current methods for accessing such compounds with a stereogenic boron center rely on chiral substrate-induced diastereoselective reactions or metal-catalyzed desymmetrization of… read more here.
Keywords: boron; iminium; center; transformation ... See more keywords
Base-promoted aerobic oxidation of N-alkyl iminium salts derived from isoquinolines and related heterocycles
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DOI: 10.1039/c9gc03629f
Abstract: Potassium tert-butoxide-promoted aerobic oxidation of N-alkyl iminium salts is reported. The reaction is atom-economical and environmentally friendly. Iminium salts derived from isoquinoline, quinoline, phenanthridine, phenanthroline, and phthalazine were successfully transformed into their corresponding unsaturated lactams… read more here.
Keywords: iminium; promoted aerobic; oxidation alkyl; iminium salts ... See more keywords
Towards depeptidized aminoboronic acid derivatives through the use of borylated iminium ions.
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DOI: 10.1039/d2cc00659f
Abstract: Herein, we use α-boryl iminium intermediates to access progressively depeptidized branched β-aminoboronic acids that are functionalized with biologically relevant heterocycles. We investigate the interaction of these novel compounds with carbohydrates under physiological conditions and demonstrate… read more here.
Keywords: derivatives use; iminium; towards depeptidized; aminoboronic acid ... See more keywords
Crystal structure and Hirshfeld surface analysis of (E)-3-[(4-chlorobenzylidene)amino]-5-phenylthiazolidin-2-iminium bromide
Sign Up to like & getrecommendations! Published in 2019 at "Acta Crystallographica Section E: Crystallographic Communications"
DOI: 10.1107/s2056989019009885
Abstract: In the crystal of the title salt, the cations and anions are linked via N—H⋯Br hydrogen bonds. In the 1H NMR spectra of this compound, the NH iminium protons are observed at δ = 10.46… read more here.
Keywords: iminium; surface analysis; hirshfeld surface; analysis chlorobenzylidene ... See more keywords
Crystal structure and Hirshfeld surface analysis of (E)-3-(benzylideneamino)-5-phenylthiazolidin-2-iminium bromide
Sign Up to like & getrecommendations! Published in 2020 at "Acta Crystallographica Section E: Crystallographic Communications"
DOI: 10.1107/s2056989020001899
Abstract: In the crystal, the cations and anions of the title salt are linked via N—H⋯Br hydrogen bonds. In the 1H NMR spectra of this compound, the NH iminium protons were observed at δ 10.35 p.p.m.,… read more here.
Keywords: iminium; surface analysis; hirshfeld surface; structure hirshfeld ... See more keywords
Recent Advances in Catalytic and Technology-Driven Radical Addition to N,N-Disubstituted Iminium Species
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DOI: 10.3390/molecules28031071
Abstract: Recently, radical chemistry has grown exponentially in the toolbox of organic synthetic chemists. Upon the (re)introduction of modern catalytic and technology-driven strategies, the implementation of highly reactive radical species is currently facilitated while expanding the… read more here.
Keywords: iminium; chemistry; catalytic technology; technology driven ... See more keywords
Synthesis of Terminal-Alkylated PEGs with Imine Spacer to Form Iminium Mono-Ion Complexes for pDNA Delivery into Skeletal Muscle
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DOI: 10.3390/pharmaceutics17081054
Abstract: Background/Objectives: To design the pDNA delivery carrier for delivery into skeletal muscle, a total of twelve terminal-alkylated PEGs (Cx-I-PEGy) with four alkyl groups of different carbon numbers (Cx: x = 4, 8, 12, 16) modified… read more here.
Keywords: skeletal muscle; pdna delivery; pdna; iminium ... See more keywords