Enantioselective Decarboxylative α-Alkynylation of β-Ketocarbonyls via a Catalytic α-Imino Radical Intermediate.
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DOI: 10.1021/acs.orglett.7b02386
Abstract: A distinctive aminocatalysis via α-imino radical is reported on the basis of SET oxidation of a secondary enamine. The combination of chiral primary amine catalysis and visible-light photoredox catalysis enables the enantioselective decarboxylative coupling of… read more here.
Keywords: imino radical; imino; ketocarbonyls; enantioselective decarboxylative ... See more keywords