A cyanide-catalyzed imino-Stetter reaction enables the concise total syntheses of rucaparib
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DOI: 10.1039/d2ra03619c
Abstract: Two routes toward the synthesis of rucaparib, an FDA-approved drug used for the treatment of ovarian and prostate cancers, have been developed from commercially available starting materials utilizing the cyanide-catalyzed imino-Stetter reaction as the key… read more here.
Keywords: stetter reaction; imino stetter; reaction; synthesis ... See more keywords
Total Syntheses of 2,2′-Biindolyl Alkaloids via Cyanide-Catalyzed Imino-Stetter Reaction
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DOI: 10.1055/a-2069-3913
Abstract: 2,2’-Biindolyl natural products have a long history of applications owing to their unique structural features and biological activities. In this account, we describe the recent progress achieved by our research group in the total syntheses… read more here.
Keywords: stetter reaction; imino stetter; reaction; catalyzed imino ... See more keywords