Serine-/Cysteine-Based sp2-Iminoglycolipids as Novel TLR4 Agonists: Evaluation of Their Adjuvancy and Immunotherapeutic Properties in a Murine Model of Asthma.
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DOI: 10.1021/acs.jmedchem.2c01948
Abstract: Glycolipids with TLR4 agonistic properties can serve either as therapeutic agents or as vaccine adjuvants by stimulating the development of proinflammatory responses. Translating them to the clinical setting is hampered by synthetic difficulties, the lack… read more here.
Keywords: serine cysteine; iminoglycolipids novel; based sp2; cysteine based ... See more keywords